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Can CBD Oil Help Treat Endometriosis? Know What The Experts Say

Can CBD Oil Help Treat Endometriosis? Know What The Experts Say

Woman suffering from endometriosis

Today, pain relief in endometriosis is a vital topic to discuss as it severely impacts women on many levels, like work, relationships, academic studies, and mental health. For the estimated 11 percent of women between 15 and 44 years old in America are living with endometriosis, symptoms like severe pain, fatigue, and nausea, and 10 to 14 percent in many countries of the world are on the same track.

Women frequently report that they can’t get endometriosis symptoms under control anyhow, even with recommended medications or surgery. For this reason, many of them are taking symptom relief into their own hands by using cannabis, and others are notably turning to cannabidiol (CBD) for pain relief.

Now you may ask- can CBD oil help treat endometriosis? Or does CBD oil work for endometriosis pain? Or how effective is CBD oil for endometriosis? To know all the answers, go through this article with patience. You can also know about CBD oil, endometriosis, the use and dosage of CBD oil for endometriosis, and research them.

What is Endometriosis Pain?

Endometriosis is an autoimmune disease relating to the abnormal growth of cells, similar to those found in the womb’s lining. According to statistics, 1 in 10 women of reproductive age is affected by the condition contributing to 176 million instances worldwide.

Women can feel severe pains in the pelvic area occurred by endometriosis. These pains are called endometriosis pains.

Common pains of endometriosis are:

  • Bladder pain
  • Heavy pain during periods
  • Consistent premenstrual pain
  • Pain in the hips, thighs, and lower back
  • Pain during sex
  • Pain with bowel movements
  • Pelvic pain
  • Leg pain

Can CBD Help With Endometriosis?

You should know that CBD isn’t a cure for endometriosis. It can help manage only some symptoms associated with the condition, including pain and cramps. Women with endometriosis are normally prescribed pain medication, hormone therapy or have to face laparoscopic surgery.

All know the undesirable side effects caused by hormonal treatments. For example, a popular hormone, Gn-RH, may trigger artificial menopause on top of causing headaches and bloating. The efficacy of NSAIDs, such as ibuprofen, is also questionable for EM-associated pain. Deutsche Arzteblatt International published a review, which shows that 70% of young women with endometriosis don’t respond to NSAID treatments.

For these reasons, as an alternative option, CBD oil is becoming more popular to treat endometriosis. Research says that CBD can help with pain and inflammation. Not much research is available on CBD and endometriosis specifically. But some women say that taking CBD oil helps soothe their pain. If you want to try it, you must check with your doctor if your CBD oil is from a safe and legal source.

cbd oil treatment for endometriosis

Research on CBD & Endometriosis

Although there isn’t any current research specifically on CBD and endometriosis pain, there are clinical trials. Although the clinical trials are not for examining the efficacy of cannabis medicine in women with endometriosis, two clinical trials investigating the effects of phytocannabinoids on endometriosis pain and related symptoms are given here.

A Spanish open-label phase II trial suggests that women with endometriosis-induced hyperalgesia will receive an oral spray with THC and CBD in a 1:1 ratio. Another is the phase III double-blind placebo study, which suggests that patients will be administered norethindrone acetate. It is a hormonal treatment supplemented with 10 mg or 20 mg of CBD to manage endometriosis pain.

A local Australian survey found that women using cannabis to treat endometriosis were getting relief in their symptoms. Gathering sufficient evidence that is strong enough to convince the medical world that cannabinoids are effective for endometriosis may take years.

In the meantime, you can see that cannabis will certainly play a significant role in the self-care routine of women throughout the world when it comes to alleviating their endometriosis pain.

How Does CBD Oil Work to Help With Endometriosis Pain?

The ECS or endocannabinoid system is a vast network of endogenous cannabinoids, enzymes, and G-coupled receptors, which work spreading throughout the body.  The receptors (type 1 and 2) work in the central nervous system, immune system, and peripheral organs. The CB1 receptor is found in pain circuits, taking part in creating pain-killing and anti-inflammatory effects. On the other hand, the CB2 receptor creates effects mostly in the immune system.

CBD oil is the most accepted form of CBD for using for endometriosis. Due to the sublingual mechanism of CBD oil, you can experience a faster onset of effects, higher bioavailability, and better absorption. The reason is that CBD enters the bloodstream directly through the tiny blood vessels in your mouth.

A 2017 study expressed how CBD and THC act on these receptors, which may be advantageous for women experiencing pain from endometriosis or other chronic pain conditions. Several studies have indicated that CBD and other cannabis compounds can help in preventing proinflammatory cytokines.

A study, which was published in Pain journal found CB1 receptors in the rodent uterus. The research showed that CB1 receptors are a potential target treatment to curb hyperalgesia in that area. The study also brought evidence that endocannabinoids and phytocannabinoids can help in alleviating endometriosis symptoms.

How to Use CBD for Endometriosis

A lot of women with endometriosis blend two forms of CBD oil, oral and topical. When taken, CBD oil, gummies, or capsules target EM symptoms from within, which plays a key role in symptom control and identifying the underlying cause. But, during endometriosis flare-ups, they may need a more localized approach, like a topical formula.

Topical products like CBD creams, gels, lotions, and salves, are applied directly onto the skin. After there, they interact with the skin’s CB2 receptors and produce a relaxing, anti-inflammatory response. This action, in turn, may contribute to effective pain control. Topicals can take between 10 and 60 minutes to start working, depending on the formulation.

Full-Spectrum vs. Isolate: Which is Better for Endometriosis?

If you focus on individual cannabinoids and their mechanisms, it will be easy to think that the cannabis plant does not have much to do when it comes to endometriosis. A passionate proponent of the entourage effect and a neuroscientist, Dr. Ethan Russo, gives importance to whole-plant cannabis medicine for treating endometriosis and other different conditions.

Russo says that the multiple components of cannabis can be put together in the right preparation to treat endometriosis. He added that it’s rare these days that one agent can successfully treat conditions like endometriosis, cancer, or even diabetes.

Conventional pharmacology isolates a compound, gives it a target, and observes how it deals with it. According to that pharmacology, it’s unlikely that one molecular mechanism will take care of the whole symptoms associated with endometriosis.

So, from the discussion, we can conclude that CBD full-spectrum is certainly better for endometriosis.

CBD Dosage for Endometriosis

Most of the modern pharmaceutical medications come out with standardized dosages, having guidelines regarding their use. But, CBD is a very personalized substance having no specific dosage for use. It can have different dosages even for people of the same height, weight, and lifestyle.

However, cannabis dosage should always start from low amounts and take time to fix the effective dosage for each individual. The main target of successful CBD dosage for endometriosis is to find the amount that can give you maximum benefits with the least side effects.

Final Thoughts

Multiple studies have shown that CBD has anti-inflammatory and analgesic properties that can be useful for endometriosis. All the cannabinoids and terpenes can interact with the endocannabinoid system, and many of them have similar anti-inflammatory and antioxidative properties. So, whole-plant extracts or full-spectrum appear to be the most effective form of cannabis treatment for endometriosis.

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